By Pierfausto Seneci
This ebook is a neurochemistry-based better half for Protein Misfolding and Neurodegenerative illnesses: Molecular Targets, an Elsevier name via an identical writer publishing in December 2014. whereas the 1st booklet specializes in biology and molecular ambitions, this spouse e-book describes how those goals are regulated through small molecules and disease-modifying compounds. The publication starts with a short creation to how key proteins turn into dysfunctional, and every next bankruptcy describes significant ailment mechanisms in Alzheimer’s and different tauopathies. houses and improvement prestige of those molecular goals and illness mechanisms are completely defined, as are small molecule effectors of autophagy and dis-aggregating brokers.
- Written to supply complete assurance of neurodegenerative disease-modifying compounds
- Provides discipline-specific chapters that disguise medicinal chemistry and scientific applications
- Provides an outline of greater than two hundred chemical sessions and lead compounds, performing on chosen molecular objectives which are of relevance to any neurodegenerative disorder
- Coverage of misfolding ailments, chaperone proteins, ubiquitination and autophagy/oncology makes this ebook compatible for structural neurochemists, chemists, biologists, non-CNS scientists, and scientists attracted to drug discovery
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Extra info for Chemical Modulators of Protein Misfolding and Neurodegenerative Disease
Chemical Modulators of Protein Misfolding and Neurodegenerative Disease by Pierfausto Seneci